Preimplantation Genetic Testing (PGT) in Pune
Advanced embryo screening technique used during IVF to detect chromosomal abnormalities before embryo transfer.
What is Preimplantation Genetic Testing?
Preimplantation Genetic Testing (PGT) is a laboratory procedure performed during IVF treatment to analyze embryos for chromosomal abnormalities before implantation. It helps identify genetically healthy embryos, improving the chances of successful pregnancy.
PGT is typically performed at the blastocyst stage after embryo development in a controlled embryology laboratory.
Types of Genetic Testing
- PGT-A: Screens for chromosomal aneuploidy.
- PGT-M: Detects specific inherited genetic disorders.
- PGT-SR: Identifies structural chromosomal rearrangements.
How PGT is Performed
After fertilization—often achieved through ICSI—embryos are cultured to the blastocyst stage. A small biopsy sample is carefully removed and sent for genetic analysis. Healthy embryos are then selected for blastocyst transfer.
This process enhances embryo selection accuracy and may reduce the risk of miscarriage.
Who Should Consider Genetic Testing?
- Couples with recurrent pregnancy loss
- Advanced maternal age
- Repeated IVF failure
- Known genetic disorders in family history
PGT is recommended after comprehensive evaluation within the broader fertility diagnosis framework.
Clinical Oversight & Laboratory Expertise
Genetic screening procedures are conducted under strict laboratory standards and supervised by experienced fertility specialists including Dr. Nikhil Gosavi, ensuring precision and ethical reproductive care.
Frequently Asked Questions
Is PGT mandatory for IVF?
No. Genetic testing is recommended in selected cases based on age, history, or medical indication.
Does PGT guarantee pregnancy?
While it improves embryo selection, success also depends on uterine health and other biological factors.
Is embryo biopsy safe?
When performed by trained embryologists, embryo biopsy is considered safe and controlled.
Can PGT detect all genetic disorders?
PGT detects specific chromosomal or known genetic abnormalities but not all possible conditions.
Does PGT increase IVF success rates?
In selected patients, PGT may improve implantation rates and reduce miscarriage risk.
