PICSI Treatment (Physiological ICSI) in Pune

Advanced sperm selection technique offered at Embryonic Fertility & IVF Centre under the embryology expertise of Dr. Nikhil Gosavi, enhancing fertilization precision in selected cases.

What is PICSI Treatment?

Physiological Intracytoplasmic Sperm Injection (PICSI) is an advanced sperm selection technique used during an IVF cycle. Unlike standard ICSI, PICSI selects sperm based on their ability to bind to hyaluronic acid — a marker of sperm maturity and DNA integrity.

How PICSI Enhances Fertilization Quality

During PICSI, sperm are exposed to a hyaluronic acid medium. Only mature sperm that naturally bind to this substance are selected for injection. This physiological selection process may reduce the likelihood of using immature sperm for fertilization.

Step-by-Step PICSI Procedure

  1. Ovarian Stimulation & Egg Retrieval: As per standard IVF protocol.
  2. Sperm Preparation: Laboratory washing and processing.
  3. Hyaluronic Acid Binding Test: Identification of mature sperm.
  4. Sperm Injection: Selected sperm injected into the egg.
  5. Embryo Culture & Transfer: Monitoring and transfer of embryo.

Who Should Consider PICSI?

PICSI may be recommended for couples experiencing recurrent IVF failure, repeated implantation failure, high DNA fragmentation, or abnormal sperm morphology. A complete evaluation through fertility diagnosis helps determine suitability.

Frequently Asked Questions

Is PICSI better than ICSI?

PICSI uses physiological sperm selection, which may be beneficial in selected male infertility cases.

Does PICSI improve embryo quality?

PICSI aims to select mature sperm, which may positively influence fertilization quality in certain cases.

Is PICSI used in every IVF cycle?

PICSI is recommended selectively based on sperm parameters and treatment history.

Is PICSI safe?

PICSI follows established embryology protocols and is considered safe when performed by experienced specialists.

When should PICSI be considered over IMSI?

The choice between PICSI and IMSI depends on sperm morphology and DNA integrity assessment.

PICSI Treatment
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